منابع مشابه
Clofibrate and fat embolism: a double-blind trial of the effects of clofibrate on sequelae to injury.
In a double-blind prospective trial clofibrate was found not to influence significantly the clinical and laboratory indices thought to reflect the state of fat embolism in patients with fractures.
متن کاملEffect of Clofibrate
Intravascular coagulation (IVC) was evaluated in 19 patients with type II and 11 with type IV hyperlipoproteinemia before and after clofibrate therapy by measurement of soluble fibrin complexes (SFC) in plasma; fibrinolysis was estimated by quantitation of fibrin (ogen) degradation products in serum. Untreated type II and type IV patients had increased SFC (P < 0.01). The former also had activa...
متن کاملEvaluation of the Effect of Oral Clofibrate Intake on Neonatal Total Serum Bilirubin: a Randomized Clinical Trial
Background: Clofibrate is a pharmacological agent, which affects the lipid metabolism. This compound could be involved in bilirubin accumulation and excretion process. Therefore, this study aimed to evaluate the effect of oral clofibrate intake on total serum bilirubin (TSB) of neonates hospitalized at Khatam Hospital. Methods: This clinical trial was conducted on 73 neonates with hyperbilirub...
متن کاملClofibrate-induced antidiuresis.
Normal subjects and patients with antidiuretic hormone (ADH) deficiency were studied to determine the mechanism of the antidiuretic action of clofibrate. Before clofibrate treatment, the patients' ability to concentrate urine with a standardized dehydration procedure correlated with the amount of ADH which was excreted. During clofibrate administration all six patients with ADH deficiency devel...
متن کاملEffects of Clofibrate and Sulfinpyrazone
Platelet survival time was measured (autologous labelling with 51chromium) in 68 men with coronary artery disease (CAD). Survival was shortened slightly (3.2 ± 0.04 days; mean ± SEM) as compared to normal (3.7 ± 0.04 days; N = 18; P < 0.001), and 60% had shortened survival (< 3.3 days). Thirty-seven had hyperlipoproteinemia (36 with Type IV and one with Type III) and platelet survival was short...
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ژورنال
عنوان ژورنال: BMJ
سال: 1972
ISSN: 0959-8138,1468-5833
DOI: 10.1136/bmj.1.5798.506-a